Published Monday, 17 September 2012
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Police officers are seaching the flat in Main Street and are also carrying out land searches in the Tyrone village.
It is believed that convicted child killer Robert Howard lived in the flat 18 years ago.
Howard was the last person to see Arlene alive on 13 August 1994 before she disappeared.
The searches are being carried out to try and locate the remains of the Tyrone schoolgirl and search for new evidence in the murder case.
This latest stage of search activity follows the receipt of new information into the investigation.
Over recent weeks work has been carried out on the derelict flat to ensure that detailed forensic activity can be conducted.
Police are hoping that modern scientific techniques may discover fresh evidence and new lines of inquiry.
The flat has been visited previously by police but this latest stage will involve more detailed forensic examination, it is not being searched for the fifteen-year-old's body.
At the same time, additional land searches are to be conducted in a stretch of countryside between Castlederg and Clady.
They will be carried out by a small team assisted by dog handlers and body recovery dogs.
A spokesman for PSNI Serious Crime Branch said: "This investigation remains active and ongoing. But it is also extremely complex and requires detectives to adopt a thorough and co-ordinated approach to progressing investigative opportunities.
"Some new information has been received. Detectives have made enquiries over the last few months to examine this information and this had led to an expansion of the existing search plan.
"The fact that new information has come into the enquiry as a result of previous appeals is heartening. Police still believe that there may be more information in the community and we would appeal for anyone with any information to come forward - for Arlene and for her family."
Arlene was last seen in the early hours of 14 August 1994. She disappeared after a night out in Bundoran.
In 2005 61-year-old Robert Howard stood trial for Arlene's murder but was acquitted.
The Arkinson family are being kept up to date about the progress of the investigation.
A police spokesman from the investigation said: "We sympathise with Arlene's family in their continued distress, frustration and anger.
"We maintain an absolute commitment to working to resolve their unbearable situation despite the complexities and timespan of the investigation."
Police have thanked landowners for their co-operation with the ongoing search operations.