The boutique programme returns from 2-27 January at the Black Box on Hill Street in Belfast city centre with a warming course of entertainment to beat the winter blues.
The musical line-up is deliciously eclectic as ever with folk, rock, blues, dub, electronica, opera and soul performances in store.
It features the likes of northern soul godfather Geno Washington, rock-hard rhymes from Scroobius Pip and Irish supergroup Four Men and a Dog.
Comedy performances lead with two Hughes - Steve and Sean, one a savagely funny and pin-sharp Aussie stand-up and the other a resurgent Irish comedy master.
Theatre will also be on the menu with the evocative Picture of Dorian Gray, Agony and Esctasy of Steve Jobs and wisdom and words from TV critic Tom Paulin, poet Paul Durcan as well as a celebration of Seamus Heaney.
Festival Director Sean Kelly said he is excited to have secured a line-up to set the pace for such a significant year in NI's cultural calendar.
"As Derry prepares to celebrate its year as Capital of Culture, we thought we'd start the year off in Belfast with possibly the greatest Festival of lunchtime arts in the world," he said.
"It is a truly exotic assembly of some of the best local, national and international artists. From Arlo Guthrie to Geno Washington, Tom Paulin to Oscar Wilde, the Jim Jones Revue to Scroobius Pip, John Shuttleworth to Lucy Porter, talks, theatre, exhibitions and even a literary bus tour, the Cathedral Quarter will be Belfast's Capital of Culture in early 2013."
Speaking ahead of the event, Belfast Lord Mayor, Alderman Gavin Robinson said: "As always, audiences can look forward to affordable entertainment to ensure lunchtimes in January will not be dull.
"I would urge everyone to go along and support the festival line-up".