The Eglinton man's blistering speed meant he broke his own championship record to win the 100m T13 well clear of the field in 10.61 on Thursday.
On Sunday he won gold in the 200m T13 final.
"Coming to a major championships is ultimately about winning, the times are irrelevant," he said.
"I'm delighted - I've put a whole lot of hard work in to this."
Sports Minister Carál Ní Chuilín congratulated the world's fastest Paralympian on his latest victory.
"There is no doubting Jason Smyth's quality as a sprinter. Clinching his second gold medal this week in record time is another excellent achievement," she said.
"Both Jason Smyth and Michael McKillop are inspirational athletes. A year on from the Olympic and Paralympic Games, it is tremendous to see our local elite athletes continuing to do so well on the world stage."