Published Friday, 01 June 2012
Sammy Clingan and Michael O'Neill in Amsterdam. (© Pacemaker)
A number of key players - including Jonny Evans, Steven Davis, Aaron Hughes and Chris Brunt - are all unavailable for the game at the Amsterdam Arena.
But O'Neill insisted: "You have to approach it the same way as you would approach a qualification game - you try and get home with some type of positive result and that's exactly how we'll approach this match."
It's great to be with the national team and coming up against some of the best players in the world, testing yourself against them.
The fixture comes ahead of away trips to Russia in September and then Portugal in October.
"The Dutch team are probably better than either of those sides," O'Neill said.
"But the experience of being out here, in such a magnificent arena to play in, will be invaluable when we go into those qualification games."
Midfielder Sammy Clingan has been installed as captain for the game against Holland, after leading his club side Coventry through a difficult season which saw them relegated from the npower Championship.
"It's much more difficult to be a captain when things are tough than when things are going well," O'Neill said, declaring Clingan the natural choice for the role.
Veteran goalie Roy Carroll is hoping for a 20th international cap - six years after his last - while Corry Evans has been forced to fly home suffering with tonsillitis.