The one-sided victory came after their 22-point win in Cavan last week.
Ireland won the series with an aggregate winning margin of 101, the highest in the history of the International Rules Series.
Ireland led 27-8 at the end of the first quarter after goals from Conor McManus and Jack McCaffrey.
Ciarán Kilkenny added a third goal at the start of the second quarter.
McManus increased Ireland's lead to 32 minutes before half-time.
Ireland led 53-16 at the break before Ciarán Sheehan and Michael Murphy landed further overs.
McManus then moved the side 71-19 ahead in the third quarter.
Ireland were 78 to 25 at the three-quarter mark before Paddy McBrearty hit their fifth goal.
Australia celebrated goals from Eddie Betts and Jake Neade but Ireland soon added a sixth thanks to Paul Conroy.
McManus finished the game as Ireland's top scorer with 24 points and was named the Player of the Series.