It could be one of the greatest comebacks ever seen on the ice at the Odyssey after the first leg of the semi final finished with the Giants 5-1 behind.
Such a lead would be almost impossible to overturn in a sport like football, but ice hockey is a bit different and coach Doug Christiansen says his team do have a chance of making the final - although he admits the odds are stacked against them.
"Of course Nottingham has an advantage, we can't deny that," he told UTV.
"But we're just focusing on winning a hockey game and if we can get to a stage later in the game where we're up a couple of goals up we might adjust tactics accordingly, but for us we just want to focus on staying on this run and when we do that we're a really good team."
The Panthers have won the Challenge Cup in each of the last three seasons and they look strong favourites to reach a fourth final following their heavy win earlier this month.
But the Giants have been on top form in the Elite League with a string of wins over the weekend, including 18 goals in their last four games.
Fans can look to those results to give them some hope of an almighty comeback on Tuesday night as the home team aim to progress to the final for the first time in four years.
The game gets underway at 7.30pm.