Eddie Patterson's Cliftonville look to stay top of the Carling Premiership.
The Reds moved three points clear when they beat Institute 4-1 on Tuesday night.
On Saturday, they go to a Newry City side which has lost three League games in a row, conceding 11 goals in the process.
Glentoran and Crusaders will be looking to capitalise on any slip from Patterson's side - however one or both of them will be disappointed as they meet each other in at the Oval.
Fourth-placed Linfield visit Lisburn Distillery who are still six points adrift at the foot of the table.
The League's leading scorer Rory Patterson will be looking to fire Coleraine to three points when they face Glenavon at Mourneview Park.
Portadown visit Dungannon Swifts as the Stangmore Park side look to bounce back from the disappointment of losing 2-0 in the Co-Operative Insurance League Cup semi-final to Coleraine on Wednesday.
Institute take on Ballymena United in an important game near the bottom.
Institute sit second from bottom, six points behind Ballymena, although the Drumahoe side do hold a match in hand.
Saturday 6th February (kick-off 3pm)
- Dungannon Swifts v. Portadown
- Glenavon v. Coleraine
- Glentoran v. Crusaders
- Institute v. Ballymena United
- Lisburn Distillery v. Linfield
- Newry City v. Cliftonville
© UTV News