Published Monday, 15 June 2009
The patient, who had underlying health problems, died in hospital in Scotland.
The death is the first to be reported outside the Americas, where there have been at least 145 fatalities of people suffering from the virus.
The patient was one of 10 being treated in hospital in Scotland and is understood to have died at the Royal Alexandra Hospital in Paisley.
A statement released by the Scottish government said: "With regret, we can confirm that one of the patients who had been in hospital, and had been confirmed as suffering from the H1N1 virus, has died."
"The patient had underlying health conditions."
A spokeswoman for the Scottish government would not confirm the gender of the person who died, nor their age.
The statement said, at the family's request, no further details would be released to allow the family time to come to terms with their loss.
Scottish health secretary Nicola Sturgeon said: "I'd like to express my condolences to the patient's family and friends."
This is a tragedy for those concerned and they have my heartfelt sympathy.
"Tragic though this death is, I would like to emphasise that the vast majority of those who have H1N1 are suffering from relatively mild symptoms."
Professor Hugh Pennington, a bacteriologist at Aberdeen University, said: "It's very sad but with the number of cases we have seen it is really something which was always going to happen sooner or later. Unfortunately it is to be expected."
"It does not point to the virus getting nastier. All the evidence to date suggests the virus is not changing at all."
"This is a flu virus, it is in no way different from an ordinary winter flu virus, so if there are enough cases some people will have to be admitted to hospital and some will die."
He said the presence of underlying health problems was likely to be a "significant factor", adding: "It makes it more likely that they will get the serious form of the virus in the first place."
A further 61 new cases in England and 35 new cases in Scotland confirmed on Sunday brought the UK total to 1,261.
There have now been 752 cases confirmed in England, 498 in Scotland, eight in Northern Ireland and three in Wales, according to figures released the Health Protection Agency and the Scottish government.