Belfast has become a popular destination for crews and a third series of HBO's Game of Thrones was filmed at the Titanic Studios in the city.
The First and deputy First Ministers pitched for further developments while in Los Angeles this week.
Mr Robinson said they want Northern Ireland to continue to develop its reputation as an excellent location for creative industries to invest
"Game of Thrones has generated up to £65m direct spend in the local economy.
"We will continue to build on our highly successful relationship with HBO and have made a strong argument for any further series to continue to be filmed in Northern Ireland," he commented.
Mr McGuinness added: "The film industry is an important sector for our economy and offers huge potential for further growth.
"HBO'S Emmy award-winning 'Game of Thrones' has created 800 jobs and contributed millions to the local economy.
"Its success provides the perfect platform to pitch for more film making projects from this important niche market."
During the trip, Mr Robinson and McGuinness also met with US President Barack Obama, as did Taoiseach Enda Kenny.
The First and deputy First Ministers discussed with Mr Obama the progress being made towards a shared future in Northern Ireland.