Published Saturday, 31 December 2011
The charity says the gifts - however small - can help raise much-needed funds for a number of overseas projects in East Africa, Kenya, Ethopia and Somalia.
Ronan O'Donnell from Oxfam is calling on people to bring the unwanted items to a local store, rather than leaving them in a drawer to gather dust.
"No matter what you get for Christmas there's always something you maybe get duplicates of," Mr O'Donnell told UTV.
"A lot of people put those things away and forget about them but by bringing them into the shops it actually does a lot of good and we're able to generate money."
Oxfam can take donations of clothes, jewellery, books, DVDs, CDs and records.
They say the only items they can't accept are electrical goods.
Head of Retail Trevor Anderson says the money raised will help the charity in their efforts to save and rebuild lives throughout the world.
"It's that whole thing of every penny counts," he said.
"If people bring one thing to us we'll make sure we raise as much money as we can for our programme overseas.
"£25 would provide clean, safe water for 175 people and £50 would support a family of six for 68 weeks with food."
So as families begin to clear-out and de-clutter after the festive period, Oxfam are hoping some of those unwanted items will make it onto their store shelves.