Published Thursday, 27 December 2012
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Harry Warwick, 78, suffers from severe dementia and police have described him as frail and vulnerable.
He was last sighted eight days ago on Wednesday, 19 December at Abingdon Manor, a nursing home on the Crumlin Road.
Eighty police officers and dozens of Mr Warwick's family and friends have been searching the area, including country parks and quarries.
Paul Warwick said: "It's been very, very difficult for the family. ..[we're] devastated he's gone.
"It's so hard, you know, the whole family's been out looking for him 'round north Belfast.
"There's just no sign."
However, Mr Warwick remains optimistic.
On Wednesday, at the Irish Premiership football match between Cliftonville and Crusaders, leaflets were handed out appealing for information.
"It's been so hard just not knowing anything at all - there's been no trace," he continued.
"I loved my uncle - that's why I'm doing everything I can to bring him home to his family.
"I just want him back.
"Even if it wasn't Christmas, it would still be hard."
Meanwhile, in Coleraine, searches have been carried out for another missing man.
Alexander McKee, who is 56 and from Limavady, was an in-patient at the Causeway Hospital.
Five days ago, he was reported missing.
It is understood he was on a heavy medication .
Over the Christmas period, his family and friends put up posters in the area. They're hoping someone might have spotted him.
Specialist search teams have been examining within a five-mile radius of where Mr McKee went missing.
They've been using dogs and a helicopter, but so far no trace of him has been found.
Mr McKee's family is increasingly worried for his safety, too.
Police would like anyone with information on the whereabouts of either Harry Warwick or Alexander McKee to come forward.
© UTV News