Over 300 youths took their own lives in the region last year - the highest ever total.
The report, 'Suicide and Homicide in Northern Ireland', found that drugs and alcohol are fuelling the problem, made worse by mental illness and social deprivation.
It said the number of suicide cases involving binge drinking in Northern Ireland was 60%, which is higher than anywhere else in the UK.
"Alcohol dependence was also the most common clinical diagnosis in patients convicted of homicide, with more than half known to have a problem prior to conviction," research author Professor Louis Appleby said.
The Royal College of Psychiatrists in NI said the study underlines the need for minimum alcohol pricing.
We welcome the recommendation in the report that pricing should be a key step towards reducing the rate of suicide.
Royal College of Psychiatrists in NI
"We can no longer afford to ignore the growing trend linking alcohol and suicide, particularly in young people," the group's Dr Uzma Huda said.
"The most straight forward action that can be taken would be to introduce a minimum unit price for alcohol. Minimum pricing has been demonstrated to have an impact on alcohol consumption of heavy drinkers, particularly younger people who binge drink."
The matter of alcohol pricing is currently out for public consultation. If measures go ahead, the minimum cost per unit of alcohol could be set between 40p and 70p in licensed premises.
Health Minister Edwin Poots said experts believe upping the price will reduce the suicide rate.
"We have alcohol being sold in some instances at considerably less than 20p per unit, so young people are binging on very cheap alcohol," Mr Poots told UTV.
"It is a depressant, and all the experts in this field believe that putting the price of that type of alcohol up will help reduce suicide."
Wednesday's report was carried out by The National Confidential Inquiry into Suicide and Homicide by People with Mental Illness, commissioned by the Public Health Agency.
It said there were a total of 1,865 deaths by suicide in Northern Ireland between 2000 and 2008, averaging 207 per year.
This level is higher than England and Wales, but lower than in Scotland.