Published Monday, 24 February 2014
Harold Ramis passed away on Monday. (© Getty)
He was best known for his role as Dr Egon Spengler in the 1984 move hit Ghostbusters and its sequel in 1989.
Ramis was also a successful writer and director with hits including Groundhog Day and Caddyshack.
More recently he had directed several episodes of the American version of The Office.
It is understand he died at his home in Chicago on Monday morning.
Following the news of his death, the United Talent Agency confirmed the actor died from complications arising from an auto-immune disease.
In a statement the Agency said: "Comedy legend Harold Ramis...died today from complications related to auto-immune inflammatory vasculitis, a condition Ramis battled for the past four years.
"Ramis passed away peacefully this morning surrounded by family and friends in his Chicago area home, where he and wife, Erica Mann Ramis, have lived since 1996. Prior to that, Ramis lived in Los Angeles for 20 years."
A number of famous faces have paid tribute to the star via Twitter.
Actor and presenter Stephen Fry wrote: "Stunned and saddened to hear of the death of Harold Ramis. A comedy hero..."
Family Guy creator Seth MacFarlane said: "Harold Ramis was a brilliant, shining example for every comedy writer hoping to achieve excellence the field. He will be sorely missed."
© UTV News