A host of gigs were planned for throughout the next couple of months, but the band say all dates are now off and there are no plans to reschedule as they're putting their music "on hold".
In a message to fans, posted on General Fiasco's social media pages, the foursome said they were going to "take some time out after more than six years and hundreds of live shows".
The band - Strathern brothers Owen and Enda, Stephen Leacock and Stuart Bell - hail from Bellaghy in Co Londonderry and started out back in 2007.
Since then, they've signed to indie label Dirty Hit and released two albums - 2010's Buildings and Unfaithfully Yours just out last year.
The band have also played festivals and gigs around the world, including Glastonbury, Reading and Leeds, T In The Park and Oxegen.
General Fiasco were the support act for fellow local act Snow Patrol, when they played the biggest concert of its kind in Northern Ireland in front of 45,000 people in Bangor's Ward Park.
But now doubt has been cast over the band's future.
"We would like to thank and apologise to everyone who had bought a ticket or had planned to come to one of the shows, as well as to those involved with organising them," they said.
"We don't make this decision lightly and we hope you understand. There are currently no plans to reschedule the dates. If anything changes we will let you know."