Dave Gahan, Martin Gore and Andy Fletcher are bringing The Delta Machine World Tour to the Odyssey Arena on 7 November.
They have also announced they will play a date at the O2 in Dublin on 9 November.
Formed in the 1980s, Depeche Mode has sold over 100 million albums worldwide. They are best known for their huge hits such as Personal Jesus and Enjoy the Silence.
With over three decades in the music business, the band has recently released their 13th studio album, Delta Machine.
Speaking about their upcoming tour, lead singer Dave Gahan said he was 'looking forward to getting out there and performing.'
"There are so many die hard Depeche Mode fans who have been with us every step of this journey that I can't wait to see. I also hope that we gain some new fans with the release of Delta Machine, and I look forward to exposing them to a great Depeche Mode live performance," he said.
Martin Gore added, "I enjoy being in front of an audience because our songs really take on a life of their own when performed live.
"When we're performing, the stage almost becomes a mirror for the people who have been there since the beginning, and we become a reflection of our audience. I'm looking forward to this tour for that very reason."
Tickets go on sale Friday 12 April at 9am.